产品描述 4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 µM for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.[1]
别名 4,9-Anhydrotetrodotoxin, 4,9-anhydro-TTX
分子量 301.25
分子式 C11H15N3O7
CAS No. 13072-89-4
存储
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度
H2O: 1 mg/mL
Ethanol: 5 mg/mL
产品描述 4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 µM for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.[1]
别名 4,9-Anhydrotetrodotoxin, 4,9-anhydro-TTX
分子量 301.25
分子式 C11H15N3O7
CAS No. 13072-89-4
存储
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度
H2O: 1 mg/mL
Ethanol: 5 mg/mL