用途 | Decamethonium Bromide |
别名 | Decamethonium Bromide |
CAS编号 | 541-22-0 |
产地/厂商 | xxjl |
Decamethonium Bromide
CAS 号:541-22-0
英文名字:Decamethonium Bromide
质量标准:>98%,BR
分子式:C16H38N2.2Br
产品描述 | Decamethonium Bromide 是一种烟碱AChR部分激动剂和神经肌肉阻断剂。 | |||||
靶点 | ||||||
IC50 | ||||||
体外研究 | Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle. In the process of binding, decamethonium actually activates (depolarizes) the motor endplate, but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release. | |||||
体内研究 | ||||||
溶解性 | DMSO 34 mg/mL,水 84 mg/mL,乙醇 25 mg/mL | |||||
稳定性 | 2年 -20°C粉状,6月-80°C溶于DMSO |
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